pKWmEB: integration of Kruskal–Wallis test with empirical Bayes under polygenic background control for multi-locus genome-wide association study
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چکیده
منابع مشابه
Using Functional Annotation for the Empirical Determination of Bayes Factors for Genome-Wide Association Study Analysis
A genome wide association study (GWAS) typically results in a few highly significant 'hits' and a much larger set of suggestive signals ('near-hits'). The latter group are expected to be a mixture of true and false associations. One promising strategy to help separate these is to use functional annotations for prioritisation of variants for follow-up. A key task is to determine which annotation...
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ژورنال
عنوان ژورنال: Heredity
سال: 2017
ISSN: 0018-067X,1365-2540
DOI: 10.1038/s41437-017-0007-4